Clonal evolution & Humanisation of PDX models

Introduction to the session

Annette T. Byrne (Royal College of Surgeons in Ireland, Dublin, Ireland), Steven de Jong (University Medical Centre Groningen, The Netherlands)

Patient-derived tumor xenografts in humanized NSG-SGM3 mice: an improved immuno-oncology platform

Li-Chin Yao (The Jackson Laboratories, USA)

Read more

Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones in humanized niche xenograft mouse leukemia models

Jan Jacob Schuringa (University Medical Centre Groningen, The Netherlands)

Read more

Heterogeneity and clinical responses to immunotherapy can be modelled and predicted using novel immune-humanized PDX models

Jonas Nilsson (Sahlgrenska Translational Melanoma Group, Sahlgrenska Cancer Center, Department of Surgery, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden)

Read more

Selected abstract: Multi-OMIC approach to unravel mechanisms of acquired resistance to docetaxel in triple negative breast cancer

Eva González Suárez (Bellvitge Institute for Biomedical Research, Spain)

Read more